’RSFTSTYLb¼ąJCell Death Discovery_222017_80648ūū,Nature Style GuideScienceūū p  pAuthor Guidelines: This style is for the journal Nature published by Nature Publishing. Author guidelines were graciously provided by the editorial department. (See notes below). Journal-specific guidelines may be found at: https://www.nature.com/documents/cddiscovery-gta.pdf Nature has requested that authors "remove" the EndNote field codes prior to submitting their articles. To do this: 1. Make a back-up copy of your manuscript 2. Open the back-up copy in Word 3. Select (Word 97-2003) Tools/EndNote/Remove Field Codes (Word 2007) Under the EndNote Ribbon, select Convert Citations and Bibliography/Convert to Plain Text and follow the prompts. Nature's format for References to online-only journals require that "either" the URL or the DOI number be placed in the reference. EndNote doesn't know how to make the distinction when both are present so we have opted to include the DOI number in our format. 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Users may wish to create a new field for supplements and modify the style accordingly. http://www.nature.com/nature/index.html St!ų"(#1$%&"(#7$%&"(#$%&"(#~$%&"(#’$%&"(#˜$%&0Cell Death Discovery6Nature Publishing Groupūūphttps://www.nature.com/documents/cddiscovery-gta.pdfD( !ppqrs…t°xTyz{  , !|  & ūū!xTyzd{  , !|  & ūū!uh}~ et al.ūū€‚, . . . ƒ„vw ---ūū!"ppqrs…t°xTyz{  , !|  & ūū!xTyzd{  , !| , & !uh}~ et al.ūū€‚, . . . ƒ„vw ---ūū!#=Ø Ą”¢°t‘’ “” •  . !–—h‘’ “” • –—t‘’ “”  . !• –—h‘’ “” • –—t‘’ “”   ūū!• –—t‘’ “”  , !• –—t‘’ “”  ūū!• –—€‘’ “”  (ūū!•  ).!–—t‘’ “”  ūū!• –— ‘+’ “”8 (https://doi.org:!• –˜˜— X”¢Ht‘’ “” •  . !–—h‘’ “” • –—t‘’ “”  . !• –—x‘’ “” •  edn!–—t‘’ “”  , !• –—|‘’ “”$ Vol. ūū!• –—t‘’ “”  ūū!• –—t‘#’ “” •  ūū!–—t‘’ “”  (ūū!• –—h‘ ’ “” • –—t‘’ “”  , !• –—h‘’ “” • –—t‘’ “”  )ūū!• –—t‘’ “”  .ūū!• –— ģ”¢Üt‘’ “” •  . !–—t‘’ “” •  ūū!–—€‘’ “” •(  thesisūū!–—t‘ ’ “”  , !• –—„‘’ “” , (ūū!•  )ūū!–—t‘’ “”  .ūū!• –— ¤”¢”t‘’ “” •  . !–—¬‘’ “” in ūū!•D  .ūū!0"(#$%&–—x‘’ “” •  edn!–—t‘’ “”  ūū!• –—‘ ’ “”, (ed^(eds ūū!•  )ūū!–—t‘’ “”  ūū!• –—h‘’ “” • –—t‘’ “”  ūū!• –—t‘’ “”  (ūū!• –—h‘ ’ “” • –—t‘’ “”  , !• –—h‘’ “” • –—t‘’ “”  )ūū!• –—t‘’ “”  .ūū!• –— (”¢t‘’ “” •  ūū!–—”‘’ “” v. ūū!•  ūū!–˜˜—t‘’ “”  (ūū!• –—h‘ ’ “” • –—t‘’ “”  , !• –—h‘ ’ “” • –—t‘’ “”  , !• –—h‘’ “” • –—t‘’ “”  ).!• –— ģ”¢Üt‘’ “” •  . !–—x‘’ “” in ūū!• –—t‘’ “”  ūū!• –—|‘’ “”$ Vol. ūū!• –—t‘’ “”  ūū!• –—h‘’ “” • –—t‘’ “”  ūū!• –—‘ ’ “”, (ed^(eds ūū!•  )ūū!–—t‘’ “”  ūū!• –—„‘#’ “” Ch. !•  ,ūū!–—t‘’ “”   ūū!• –—t‘’ “”  ūū!• –—t‘’ “”  (ūū!• –—t‘ ’ “” •  , !–—h‘’ “” • –—t‘’ “”  )ūū!• –—t‘’ “”  .ūū!• –— ü” ¢ģt‘’ “” •  . !–—t‘’ “” •  . !–—˜‘’ “”0 Report No. ūū!• –˜˜ —t‘’ “”  , !• –—t‘’ “” •  ūū!–—t‘’ “”  (ūū!• –—h‘ ’ “” • –—t‘’ “”  , !• –—h‘ ’ “” • –—t‘’ “”  , !• –—h‘’ “” • –—t‘’ “”  )ūū!• –—t‘’ “”  .ūū!• –— č”¢Ųt‘’ “” •  . !–—t‘’ “” •  . !–—€‘ ’ “” •(  patent !–—t‘’ “” •  ūū!–—€‘’ “”  (ūū!•  )ūū!–—t‘’ “”  .ūū!• –— l”¢\t‘’ “” •  . !–—t‘’ “” •  , !–—„‘’ “”  <ūū!• > (ūū!–—t‘’ “” •  )ūū!–—t‘’ “”  .ūū!• –—  ”¢t‘’ “” •  . !–—h‘’ “” • –—t‘’ “”  . !• –—h‘’ “” • –—t‘’ “”   ūū!• –—t‘’ “”  , !• –—€‘’ “”   (!•  )ūū!–—t‘’ “”  . !• –—€‘’ “”  <ūū!•  >ūū!–—t‘’ “”  .ūū!• –— h”¢Xt‘’ “” •  . !–—x‘’ “” in ūū!• –—t‘’ “”  ūū!• –—|‘’ “”$ Vol. ūū!• –—t‘’ “”  ūū!• –—h‘’ “” • –—t‘’ “”  ūū!• –—‘ ’ “”, (ed^(eds ūū!•  )ūū!–—t‘’ “”   ūū!• –—t‘’ “”  ūū!• –—t‘’ “”  (ūū!• –—t‘ ’ “” •  , !–—t‘ ’ “” •  , !–—h‘’ “” • –—t‘’ “”  )ūū!• –—t‘’ “”  .ūū!• –— Œ”%¢|t‘’ “” •  . !–—t‘’ “” •  ūū!–—t‘’ “”  (ūū!• –—œ‘’ “”4 $Catalogue No. !• –˜˜—t‘’ “”  , !• –—h‘ ’ “” • –—t‘’ “”  , !• –—h‘ ’ “” • –—t‘’ “”  , !• –—h‘’ “” • –—t‘’ “”  )ūū!• –—t‘’ “”  .ūū!• –—$äh‘@’ “” • –—t‘’ “”  ūū!• –—%'(°±²³&e()T|t‘+’ “”   ūū!• –—|t‘"’ “”  , !• –—„|‘’ “”$ , doi:!• –—°Ø‘’ “”P >, edited and translated by ūū!• –—*@ä0  ,ūū!213ˆ €”¢ph‘@’  “” • –—Aü ō”¢ät‘’ “” •   ūū!–—h‘@’  “” • –—4hpqrs…tøxXyzd{  , !|$  and ūū!xXydzd{  , !|$  and ūū!uh}~, et al.€‚, . . . ƒ„vw B$  and ūū!C$  and ūū!5(°±²³64ŠŃŅ  -ūū!7dąį  ; !āåęē č 8h}~, et al.€‚, . . . ƒ„9:;  , !<=>?@ ¼PQZ  ; !RSxpqrs…tøxXyzd{  , !|$  and ūū!xXydzd{  , !|$  and ūū!uh}~, et al.€‚, . . . ƒ„vw ---ūū!Txpqrs…tøxXyzd{  , !|$  and ūū!xXydzd{  , !|$  and ūū!uh}~, et al.€‚, . . . ƒ„vw ---ūū!UVWY,ĄĮĀĆÄ$ Ibid.!Ģ„|‘’ “”$ Ibid.ūū!• –—Å$ Ibid.!ĘĒ ČÉ ŹSxpqrs…tøxXyzd{  , !|$  and ūū!xXydzd{  , !|$  and ūū!uh}~, et al.€‚, . . . ƒ„vw ---ūū!Txpqrs…tøxXyzd{  , !|$  and ūū!xXydzd{  , !|$  and ūū!uh}~, et al.€‚, . . . ƒ„vw ---ūū!ĖU[L|t‘+’ “”  , !• –—|t‘"’ “”  , !• –—|t‘’ “”  , !• –—°Ø‘’ “”P >, edited and translated by ūū!• –—  `ab<dc, Anonymousūū!(@ABC `šńņóōõö÷ųłś